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Links Medical Genetics University of Calgary
Dr. Jeptha Davenport 
Assistant Professor
Departments of Biochemistry & Molecular Biology / Medical Genetics
Health Sciences Centre, University of Calgary 
Tel: (403) 210-8713   Fax: (403)270-0737
Email: 


Research Interests


One of the key questions of developmental biology is how organs are formed and how genes control this process. To understand this complex process I am studying the development of a simple organ: the pharynx of the nematode C. elegans.
he pharynx is a bilobed, neuromuscular organ that pumps food in from the environment and initiates digestion. My particular interest is in identifying new genes that regulate development of the pharynx. I have used bioinformatics to find regulatory elements in pharynx genes and am now working to identify the transcription factors that function through them. Once identified, the study of these factors will shed light on how cells are instructed to make organs.


Publications

Raharjo, I. and J. Gaudet. Gland-specific expression of C. elegans hlh-6 requires the combinatorial action of three distinct promoter elements.  Dev Biol, 302: 295-308 (2007)
 

Research Funding

CIHR
  • “C. Elegans pharyngeal glands” 2007-2012
  • “Computational and biological analysis of regulators of pharynx development in C. elegans”. 2004-2007

Canadian Foundation for Innovation
  • “Generation of a C. elegans facility to study genetic regulators of organ foundation”. 2004 2007; 2006-2011


Natural Sciences and Engineering Research Council of Canada

  • “Specification of digestive tract gland cells in C. elegans”. 2006 – 2011

Heritage Research Foundation for Medical Research
Alberta
  • “Request for biolistic transformation equipment”. 2006-2007
  • “Computational and biological analysis of regulators of pharynx development in C. elegans”. 2004-2006
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