Dr. Jeptha Davenport
Assistant Professor
Departments of Biochemistry & Molecular Biology / Medical Genetics
Health Sciences Centre, University of Calgary
Tel: (403) 210-8713 Fax: (403)270-0737
Email:
Research Interests
One of the key questions of developmental biology is how organs are formed and how genes control this process. To understand this complex process I am studying the development of a simple organ: the pharynx of the nematode C. elegans. he pharynx is a bilobed, neuromuscular organ that pumps food in from the environment and initiates digestion. My particular interest is in identifying new genes that regulate development of the pharynx. I have used bioinformatics to find regulatory elements in pharynx genes and am now working to identify the transcription factors that function through them. Once identified, the study of these factors will shed light on how cells are instructed to make organs.
Publications
Raharjo, I. and J. Gaudet. Gland-specific expression of C. elegans hlh-6 requires the combinatorial action of three distinct promoter elements. Dev Biol, 302: 295-308 (2007)
Research Funding
CIHR
Canadian Foundation for Innovation
Natural Sciences and Engineering Research Council of Canada
- “Specification of digestive tract gland cells in C. elegans”. 2006 – 2011
Heritage Research Foundation for Medical ResearchAlberta